For pharma & research

Objective digital endpoints.

Run decentralised trials on exploratory, real-world research measures of quality of life and disease progression. Improve compliance, capture richer longitudinal evidence, and cut the cost of site visits — using everyday consumer devices.

Discuss a study → Validation & methods
96%
of participant-days captured passively, reducing missing data
40+
research measures, available as exploratory endpoints
↓
fewer site visits — lower burden for participants and sites alike

The measures on this page are research measures for use in clinical studies. They are not part of the CE-marked PARKIWATCH medical device, whose intended purpose is limited to the validated kinematic measures of tremor, bradykinesia and dyskinesia.

The measures

A library of real-world signal.

Continuous, passively-collected measures across motor, sleep and physiology — the substrate for objective digital endpoints.

Gait — cadence
Steps per minute during ambulation, day over day.
Motor
Gait — stride
Stride length and variability as a marker of stability.
Motor
Rest tremor
Amplitude and duration of tremor at rest.
Motor
Action tremor
Tremor during voluntary movement.
Motor
Activity volume
Daily active minutes and movement intensity.
Motor
Turning
Turn speed and smoothness during daily movement.
Motor
Sleep duration
Total nightly sleep and consistency.
Sleep
Sleep efficiency
Proportion of time in bed actually asleep.
Sleep
Nocturnal movement
Restlessness and awakenings overnight.
Sleep
Rest rhythm
Regularity of rest–activity cycles.
Sleep
Resting heart rate
Daily resting HR and trend.
Physiology
Heart-rate variability
Autonomic regulation over time.
Physiology
HR response
Heart-rate response to activity and recovery.
Physiology
Q-index
Composite measure of quality-of-life trend.
Composite
Symptom stability
Day-to-day variability across motor domains.
Composite
Progression slope
Longitudinal direction of change over months.
Composite

The measures on this page are research measures for use in clinical studies. They are not part of the CE-marked PARKIWATCH medical device, whose intended purpose is limited to the validated kinematic measures of tremor, bradykinesia and dyskinesia. Measure availability and endpoint qualification depend on study design and regulatory context.

Why it matters

Richer evidence, less burden.

Episodic clinic assessments miss the day-to-day reality of living with Parkinson’s. Continuous, passive capture turns months of real life into analysable signal.

  • ✓Better compliance — passive capture lowers participant burden.
  • ✓Real-world validity — measures reflect everyday function, not a single supervised test.
  • ✓Lower cost — fewer in-person site visits for participants and sponsors.
  • ✓Longitudinal depth — continuous data reveals slopes and patterns episodic visits cannot.

Design your next study around real life.

Tell us about your programme and we’ll map the measures that fit.

Discuss a study → See publications